Videomicroscopy as a tool for investigation of the microcirculation in the newborn

摘要: The perinatal period remains a time of significant risk death or disability. Increasing evidence suggests that this depends on microcirculatory behavior. Sidestream dark-field orthogonal polarized light videomicroscopy (OPS) has emerged as useful assessment adult microcirculation but the values derived are not delineated for newborn. We aimed to define these parameters in well term newborn infants. Demographic details were collected prospectively 42 healthy neonates (n = 20 females, n = 22 males). OPS (Microscan) was used view ear conch skin at 6, 24, and 72 h age. Stored video analyzed by masked observer using proprietary software. There no differences between sexes any structural point. increase over small vessel perfusion female infants only (P = 0.009). A number 6- 72-h measurements significantly correlated, differed from 24-h values. These observations confirm utility neonatal microvascular videomicroscopy. They provide baseline studies into use changes observed comparable with previous other techniques. It is recommended examining mature structure be delayed until life, physiology cardiovascular transition should include point after delivery.