Moderator's view: Higher serum bicarbonate in dialysis patients is protective.

摘要: Several observational studies have reported an association between higher serum bicarbonate level and high mortality risk in dialysis patients. However, such mere discovery of associations does not allow one to infer causal relationships. This may be related inadequate dietary protein intake that lead less acid generation hence a level. Since undernutrition is strong predictor death hemodialysis patients, the observed epiphenomenon biologically plausible relationship. Higher fluid two subsequent treatments lower low appear protective, as patients with food better appetite generally exhibit greater survival. In contemporary three-stream proportioning system treatment, concentrate separate from concentrate, contribution organic (acetate, citrate or diacetate) delivered pool patient negligible. The concept 'total buffer' assumes combination acetate concentrations dialysate are added equally equivalents likely wrong based on misleading notion fully metabolized dialysate. Given these uncertainties it prudent avoid excessively levels