Heat Shock Proteins in Thermotolerance and Other Cellular Processes

摘要: Summary Heat shock proteins appear to be causatively involved in the acquisition of thermotolerance prokaryotes but not eukaryotes. Further, enhanced synthesis hsps may necessary for some cellular responses stress others. In prokaryotic cells development thermotolerance, as measured by cell survival, is dependent upon protein synthesis. However, eukaryotes, hsp following an inducing and prior a subsequent heat neither nor sufficient colony-forming assays. The expression required mammalian responses, such ability reform both actin microfilament bundles nucleolar morphology. These latter two thermotolerant have been correlated with ability. Future work should address relationships between these various physiological determine if function repair mode regard colony formation responses. Evidence accumulating that or their cognates growth differentiation manner yet fully explained. Recent studies indicate genes controlling division E. coli linked those several regulons (104), it would surprising find similar relationship At this time, important investigating role other define specific gene (including its regulatory sequences) encodes being investigated, order avoid apparently contradictory confusing reports expression.