Tackling Australia's future health problems: developing strategies to combat sarcopenia--age-related muscle wasting and weakness.

摘要: Some of the most serious consequences ageing are its effects on skeletal muscle structure and function. Ageing is associated with a progressive loss mass (sarcopenia), slowing movement, decline in strength; factors that increase risk injury from sudden falls reliance frail elderly for assistance accomplishing even basic tasks required independent living. From public health perspective, sarcopenia has widespread clinical implications. As proportion older persons population continues to grow, will have dramatic impact lives Australians place increasing demands care. Although it generally agreed deleterious inevitable, debate exists as whether these intrinsic changes immutable or reversible. There clearly profound need therapeutic strategies can slow function, restore size strength so their quality life be maintained improved. Physical activity plays an important role ageing, but exercise alone not prevent gradual Other factors, such age-related circulating levels anabolic hormones growth must also considered when developing combat sarcopenia. Much research needed test safety efficacy exciting experimental before they recommended application.