A possible secondary role for thymine-containing DNA precursors.

作者: Robert J. Melamede , Susan S. Wallace

DOI: 10.1007/978-1-4613-2449-2_5

关键词:

摘要: Multienzyme complexes are involved in DNA replication and have been described both uninfected [50] T4-infected [59] Escherichia coli. These comprise a variety of proteins including binding, unwinding, priming, polymerizing activities. The existence multienzyme for generating precursors and/or channeling such has also demonstrated several systems [41, 52, 63, 65, 80, 96, 97] cells [4, 5, 20, 21, 38, 66, 71, 73, 74, 94, 95, 103, 106, 115, 116]. presence precursor complex greatly reduces the diffusion sequentially synthesized reactants results an efficient funneling to apparatus [94]. nature coupling between production utilization during synthesis not yet established.

参考文章(117)
W.E. Razzell, P. Casshyap, SUBSTRATE SPECIFICITY AND INDUCTION OF THYMIDINE PHOSPHORYLASE IN ESCHERICHIA COLI. Journal of Biological Chemistry. ,vol. 239, pp. 1789- 1793 ,(1964) , 10.1016/S0021-9258(18)91259-7
C.S. Chiu, T. Ruettinger, J.B. Flanegan, G.R. Greenberg, Role of deoxycytidylate deaminase in deoxyribonucleotide synthesis in bacteriophage T4 DNA replication. Journal of Biological Chemistry. ,vol. 252, pp. 8603- 8608 ,(1977) , 10.1016/S0021-9258(19)75263-6
C A Lunn, V Pigiet, Characterization of a high activity form of ribonucleoside diphosphate reductase from Escherichia coli. Journal of Biological Chemistry. ,vol. 254, pp. 5008- 5014 ,(1979) , 10.1016/S0021-9258(18)50553-6
Chitra Biswas, Jennifer Hardy, William S. Beck, Release of repressor control of ribonucleotide reductase by thymine starvation. Journal of Biological Chemistry. ,vol. 240, pp. 3631- 3640 ,(1965) , 10.1016/S0021-9258(18)97191-7
James L. Farmer, Frank Rothman, Transformable Thymine-Requiring Mutant of Bacillus subtilis Journal of Bacteriology. ,vol. 89, pp. 262- 263 ,(1965) , 10.1128/JB.89.1.262-263.1965
H Nakayama, P Hanawalt, Sedimentation analysis of deoxyribonucleic acid from thymine-starved Escherichia coli. Journal of Bacteriology. ,vol. 121, pp. 537- 547 ,(1975) , 10.1128/JB.121.2.537-547.1975
M G Wovcha, C S Chiu, P K Tomich, G R Greenberg, Replicative bacteriophage DNA synthesis in plasmolyzed T4-infected cells: evidence for two independent pathways to DNA. Journal of Virology. ,vol. 20, pp. 142- 156 ,(1976) , 10.1128/JVI.20.1.142-156.1976