High performance liquid chromatography determined alkamide levels in Australian-grown Echinacea spp

摘要: Summary. Extracts of Echinacea spp. are widely used as therapeutic immunostimulants with such activity being attributed in part to the alkamide fractions these plants. Using high performance liquid chromatography, levels 8 alkamides, including 2 tetraene alkamides (dodeca-2E, 4E, 8Z, 10E/Z-tetraenoic acid isobutylamide), were quantitatively determined Australian-grown Overall, E. angustifolia found be comparable obtained this study and other studies for USA European However, results one sample suggested that it may have been mislabelled was most likely a pallida. Levels purpurea also similar to, if not higher, than which reported same species grown Germany USA. Preliminary on stability compounds indicated they susceptible degradation, 13% loss level over months. indicate there is considerable potential develop viable crop Australia.