A case of atypical teratoid/rhabdoid tumor in an adult, with long survival

摘要: Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant that mostly occurs in early childhood and has poor prognosis despite aggressive therapy. Adult cases are rare and, as far we aware, only 30 have been reported to date. Here present the case of 27-year-old female with left parietal AT/RT chief complaint numbness right superior limb. First, was surgically removed diagnosis grade II glioma. With additional radiotherapy, clinical course after surgery favorable. After 6 years, she had an operation for recurrence III Temozolomide prescribed, disease-free period 2 years followed. Surgery performed third time second histology diffuse growth rhabdoid cells. Immunohistochemistry partially positive vimentin epithelial membrane antigen. Ki-67 labeling index extremely high cells showed no staining INI1 suggestive AT/RT. We re-evaluated past specimens none immunoreactivity INI1. O-6 methylguanine DNA methyltransferase (MGMT) were also re-examined both increased gradually. She still alive without more than 1 year. As this longest survival adult