Relation of Left Ventricular Midwall Function to Cardiovascular Risk Factors and Arterial Structure and Function

摘要: Abstract —Left ventricular (LV) midwall shortening (MWS) is subnormal in relation to LV circumferential end-systolic stress (ESS) (ESS-corrected MWS) many hypertensive patients with normal chamber function and predicts subsequent morbidity mortality. However, little known of the relations demographic metabolic variables or arterial geometry. Asymptomatic, unmedicated normotensive (n=366) (n=282) adults were assessed echocardiography carotid ultrasound. In adults, lower MWS ESS-corrected MWS, an index contractility, related independently high total peripheral resistance, heart rate, male gender (all P =.001) diastolic pressure ( =.003), for only, relative wall thickness (RWT, =.03). Among patients, values both indices associated higher resistance =.04), as well =.0006) RWT =.009); =.004), =.042), systolic artery expansion =.032). Lower entire population was rate (both =.0006), =.004); gender; =.006), serum HDL cholesterol levels =.04). a subset (n=60), positively apolipoprotein A1 =.004) negatively hemoglobin A1c