Karela: A promising antidiabetic vegetable therapy

作者: Ashok K. Tiwari

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摘要: FOOD items are now being recognized not just as a source of chemical energy, but they also possess ingredients that help reduce the risk chronic lifestyle-related diseases like diabetes, heart disease, atherosclerosis, hypertension, arthritis, cancer, allergies and related abnormal modalities. Our increased scientific understanding health benefits key components food has fuelled this renaissance 1 . This global is nothing resurgence ancient Chinese dogma ‘Medicine isogenic’ 2 doctrine Hippocrates (460‐ 377 BC), ‘Let be thy medicine food’ 3 These statements belief still continue in form traditional system medicine, particularly developing countries. Ayurveda, Indian systems an integral part culture 4 , continues to provide care large percentage our people 5 Modern analysis described classical texts ayurveda renovated justify claims made age-old classics. In ayurveda, karela (Momordica charantia Linn.) [Karavellan (Sanskrit), bitter gourd or melon (English)], grouped under vegetable class ( ) claimed several therapeutic properties. The compendia medicinal plants called Nighantus were written between 7th 17th centuries AD 6 Kaiyadeva Nighantu 7 Bhava Prakash 8 date 1500 1600 compilation these known Ratnakar 9 was 1867. describe following properties:

参考文章(35)
R. K. Sogani, R. B. Arora, V. N. Sharma, K. P. Bhargava, Some observations on hypoglycaemic activity of Momordica charantia. Indian Journal of Medical Research. ,vol. 48, pp. 471- 477 ,(1960)
S. Subramanian, D. Sathish Sekar, K. Sivagnanam, Antidiabetic activity of Momordica charantia seeds on streptozotocin induced diabetic rats. Die Pharmazie. ,vol. 60, pp. 383- 387 ,(2005)
M S Akhtar, Trial of Momordica charantia Linn (Karela) powder in patients with maturity-onset diabetes. Journal of Pakistan Medical Association. ,vol. 32, pp. 106- 107 ,(1982)
Abhishek Tongia, Mangala Dave, Sudhir Kumar Tongia, Phytochemical determination and extraction of Momordica charantia fruit and its hypoglycemic potentiation of oral hypoglycemic drugs in diabetes mellitus (NIDDM). Indian journal of physiology and pharmacology. ,vol. 48, pp. 241- 244 ,(2004)
Gail B. Mahady, Global Harmonization of Herbal Health Claims The Journal of Nutrition. ,vol. 131, pp. 1120S- 1123S ,(2001) , 10.1093/JN/131.3.1120S
J. Welihinda, E.H. Karunanayake, M.H.H. Sheriff, K.S.A. Jayasinghe, Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. Journal of Ethnopharmacology. ,vol. 17, pp. 277- 282 ,(1986) , 10.1016/0378-8741(86)90116-9
Hideyuki MATSUURA, Chikako ASAKAWA, Masanori KURIMOTO, Junya MIZUTANI, α-Glucosidase Inhibitor from the Seeds of Balsam Pear (Momordica charantia) and the Fruit Bodies of Grifola frondosa Bioscience, Biotechnology, and Biochemistry. ,vol. 66, pp. 1576- 1578 ,(2002) , 10.1271/BBB.66.1576
I. Ahmed, E. Adeghate, E. Cummings, A.K. Sharma, J. Singh, Beneficial effects and mechanism of action of Momordica charantia juice in the treatment of streptozotocin-induced diabetes mellitus in rat Molecular and Cellular Biochemistry. ,vol. 261, pp. 63- 70 ,(2004) , 10.1023/B:MCBI.0000028738.95518.90