Synthesis and Heteroannulation of Pyridine and Related Heterocyclic Systems Having Surface and Biological Activities.

摘要: Possible approaches to the synthesis of functionalized, pyrazole, isoxazole, pyrimidine, pyridine and fused derivatives The sequence involves heterocyclization ethyl 3-oxo-2-(4-stearamidobenzoyl)butanoate (3) with appropriate reagents. Propoxylated these heterocycles using propylene oxide produce nonionic surface active agents having a long alkyl chain molecular weight suitable for becoming an amphiphilic molecule correct hydrophilic-lypophilic balance which enhances solubility, biodegradability hence lowers toxicity human beings becomes environmentally friendly. antimicrobial activity newly synthesized was examined it found that some compounds have similar or higher compared commercial antibiotic drugs (sulphadiazine), make them diverse applications like manufacturing drugs, pesticides, emulsifiers, cosmetics, etc.