Side chain metalation of (5-substituted-2-furyl)oxazolines
作者： Jean-Yves Lenoir , Pierre Ribéreau , Guy Quéguiner
DOI: 10.1016/S0040-4039(00)73412-5
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摘要: Abstract Side chain metalation at the 5-methyl or 5-benzyl position of 4,4-dimethyl-2-(5-substituted-2-furyl)oxazolines has been achieved using butyllithium as metalating agent and THF-HMPA 4:1 solvent. The lithiated species can be reacted with various electrophiles to give expected products in good yields.
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