Disparate Companions: Tissue Engineering Meets Cancer Research

摘要: Recreating an environment that supports and promotes fundamental homeostatic mechanisms is a significant challenge in tissue engineering. Optimizing cell survival, proliferation, differentiation, apoptosis angiogenesis, providing suitable stromal support signalling cues are keys to successfully generating clinically useful tissues. Interestingly, those components often subverted the cancer setting, where aberrant cellular resistance drive malignant growth. In contrast engineering, identifying inhibiting pathways major research. The recent discovery of adult tissue-specific stem cells has had impact on both engineering unique properties these their role organ repair regeneration hold great potential for constructs. emerging body evidence implicating progenitor as source oncogenic transformation prompts caution when using tissue-engineering purposes. While research may be considered opposed fields with regard proclaimed goals, compelling overlap underlying processes suggests cross-disciplinary will benefit fields. this review article, brought together explored discoveries mutual benefit.