Convergent Loss of an EDS1/PAD4 Signaling Pathway in Several Plant Lineages Reveals Coevolved Components of Plant Immunity and Drought Response.

摘要: Plant innate immunity relies on nucleotide binding leucine-rich repeat receptors (NLRs) that recognize pathogen-derived molecules and activate downstream signaling pathways. We analyzed the variation in NLR gene copy number identified plants with a low of genes relative to sister species. specifically focused four from two distinct lineages, one monocot lineage (Alismatales) eudicot (Lentibulariaceae). In these loss coincides well-known immune complex ENHANCED DISEASE SUSCEPTIBILITY 1 (EDS1)/PHYTOALEXIN DEFICIENT 4 (PAD4). expanded our analysis across whole proteomes found other characterized were absent only Lentibulariaceae Alismatales. Additionally, we unknown function convergently lost together EDS1/PAD4 five plant Gene expression analyses Arabidopsis (Arabidopsis thaliana) Oryza sativa revealed several homologs candidates are differentially expressed during pathogen infection, drought, abscisic acid treatment. Our provides evolutionary evidence for rewiring some as well coevolution pathway drought responses.