Continuous synthesis of glycogen by individual worm pairs of Schistosoma mansoni inside the veins of the final host.

摘要: Hamsters infected with Schistosoma mansoni were operated upon to install a permanent canula into their blood stream. After recovery of the hamster, this was used for injection radioactively labelled glucose. In way glycogen metabolism S. could be studied while parasites remained undisturbed in natural habitat. The consecutive [U-14C]glucose and [1-3H]glucose permitted an analysis possible changes synthesis individual worm pairs time. results showed that by each pair fairly constant Furthermore, all synthesised continuously; not even 2 min passed without its formation. Only small differences observed between isolated from different locations veins hamster. These exclude possibility had alternating periods degradation, they also disprove idea degradation occur at two sites bloodstream experiments further proportional amount already present, which turn shown size parasite. From study it can concluded replenishment endogenous reserves is induced marked decrease levels, but occurs slowly continuously.