Ortho substituted aromatic compounds useful as antagonists of the pain enhancing effects of E-type prostaglandins
作者： Peter Warner , Howard Tucker , Gloria Ann Breault , John Oldfield
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摘要: The invention relates to compounds of the formula (I): ##STR1## wherein A, B and D are various ring systems such as phenyl, R 1 includes carboxy, 3 is hydrogen or C 1-4 alkyl Z a linking group --(CH(R 5 )) m -- 2, 4, methyl; pharmaceutically acceptable salts in vivo hydrolysable esters amides thereof, processes for preparing these compounds, pharmaceutical compositions comprising them, their use treatment pain.
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