Intracochlear near infrared stimulation: Feasibility of optoacoustic stimulation in vivo.
作者： Peter Baumhoff , Nicole Kallweit , Andrej Kral
DOI: 10.1016/J.HEARES.2018.11.003
关键词:
摘要: Abstract Intracochlear optical stimulation has been suggested as an alternative approach to hearing prosthetics in recent years. This study investigated the properties of a near infrared laser (NIR) induced optoacoustic effect. Pressure recordings were performed at external meatus anaesthetized guinea pigs during intracochlear NIR stimulation. The sound pressure and power spectra determined. results compared multi unit responses inferior colliculus (IC). Additionally, IC by electric same cochlear position investigate potentially confounding contribution direct neural recorded (n = 7) had most frequencies below 10 kHz showed little variation for different sites. mean spike rates units responding (n = 222) 17 animals significantly correlated with externally signal corresponding best units. response strength well depended on pulse peak stimulus. reached levels above 70 dB SPL equivalent. In activation apical location fiber was found. absence any after pharmacologically deafening comparison site revealed no indication might become useful combined electro-acoustic devices future.
sci-hub.se 参考文章(40)
John C. Middlebrooks, Julie Arenberg Bierer, Auditory cortical images of cochlear-implant stimuli: coding of stimulus channel and current level. Journal of Neurophysiology. ,vol. 87, pp. 493- 507 ,(2002) , 10.1152/JN.00211.2001
Peter Dallos, The Auditory Periphery Biophysics and Physiology ,(1973)
Pascal Magnan, Paul Avan, Armand Dancer, Jacek Smurzynski, Rudolf Probst, Reverse middle-ear transfer function in the guinea pig measured with cubic difference tones. Hearing Research. ,vol. 107, pp. 41- 45 ,(1997) , 10.1016/S0378-5955(97)00015-4
Kent F. Palmer, Dudley Williams, Optical properties of water in the near infrared. Journal of the Optical Society of America. ,vol. 64, pp. 1107- 1110 ,(1974) , 10.1364/JOSA.64.001107
Rohit U. Verma, Amélie A. Guex, Kenneth E. Hancock, Nedim Durakovic, Colette M. McKay, Michaël C.C. Slama, M. Christian Brown, Daniel J. Lee, Auditory responses to electric and infrared neural stimulation of the rat cochlear nucleus. Hearing Research. ,vol. 310, pp. 69- 75 ,(2014) , 10.1016/J.HEARES.2014.01.008
Alexander C. Thompson, Scott A. Wade, William G. A. Brown, Paul R. Stoddart, Modeling of light absorption in tissue during infrared neural stimulation Journal of Biomedical Optics. ,vol. 17, pp. 075002- ,(2012) , 10.1117/1.JBO.17.7.075002
Suhrud M. Rajguru, Agnella Izzo Matic, Alan M. Robinson, Andrew J. Fishman, Laura E. Moreno, Allison Bradley, Irena Vujanovic, Joe Breen, Jonathon D. Wells, Mark Bendett, Claus-Peter Richter, Optical cochlear implants: evaluation of surgical approach and laser parameters in cats. Hearing Research. ,vol. 269, pp. 102- 111 ,(2010) , 10.1016/J.HEARES.2010.06.021
Russell L. Snyder, Julie A. Bierer, John C. Middlebrooks, Topographic Spread of Inferior Colliculus Activation in Response to Acoustic and Intracochlear Electric Stimulation Jaro-journal of The Association for Research in Otolaryngology. ,vol. 5, pp. 305- 322 ,(2004) , 10.1007/S10162-004-4026-5
C.-P. Richter, A.I. Matic, J.D. Wells, E.D. Jansen, J.T. Walsh, Neural stimulation with optical radiation. Laser & Photonics Reviews. ,vol. 5, pp. 68- 80 ,(2011) , 10.1002/LPOR.200900044
Laura E. Moreno, Suhrud M. Rajguru, Agnella Izzo Matic, Nitin Yerram, Alan M. Robinson, Margaret Hwang, Stuart Stock, Claus-Peter Richter, Infrared neural stimulation: beam path in the guinea pig cochlea. Hearing Research. ,vol. 282, pp. 289- 302 ,(2011) , 10.1016/J.HEARES.2011.06.006