An 18-mer Peptide Derived from Prosaposin Ameliorates the Effects of Aβ1-42 Neurotoxicity on Hippocampal Neurogenesis and Memory Deficit in Mice.

作者: Hui-ling Gao , Cheng Li , Hiroaki Nabeka , Tetsuya Shimokawa , Zhan-You Wang

DOI: 10.3233/JAD-160093

关键词:

摘要: … Treatment with PS18 attenuated these effects evoked by Aβ 1–42 . Our data … hippocampal neurogenesis caused by Aβ 1–42 -induced neuroinflammation and prevented memory deficits …

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