Antibacterial properties and compressive strength of new one-step preparation silver nanoparticles in glass ionomer cements (NanoAg-GIC).

摘要: Abstract Objectives This work aimed (1) to develop polyacid formulations by the one-step photoreduction of silver nanoparticles (AgNP) in a polyacrylate solution conventional glass ionomer cement (GIC), imparting antibacterial activity; and (2) evaluate handling mechanical properties experimental ionomers comparison commercially available GIC. Methods Formulations with increasing sub-stoichiometric amounts AgNO3 were monitored during continuous UV light exposure UV–vis spectroscopy analyzed transmission electron microscopy. The resulted synthesis containing small disperse spherical (∼6 nm) used design nano-silver cements (NanoAg-GIC). characterized as net setting time compressive strength according ISO 9917-1:2007 specifications. activity these was assessed Ag+ diffusion tests on nutritive agar plates (E. coli) MTT assay (S. mutans). Results higher concentration (0.50% mass) matrix NanoAg-GIC allowed viable increased 32% cement. All groups AgNP induced statistically significant E. coli growth inhibition zones (p-value Conclusions Silver preparation production highly bioactive water-based within suitable parameters for clinical use large potential dental biomedical application.