Acute stress alters autonomic modulation during sleep in women approaching menopause.

摘要: Hot flashes, hormones, and psychosocial factors contribute to insomnia risk in the context of menopausal transition. Stress is a well-recognized factor implicated pathophysiology insomnia; however impact stress on sleep sleep-related processes perimenopausal women remains largely unknown. We investigated effect an acute experimental (impending Trier Social Task morning) pre-sleep measures cortisol autonomic arousal with without that developed In addition, we assessed macro- micro-structure functioning during sleep. Following adaptation laboratory, twenty two (age: 50.4 ± 3.2 years) eighteen 48.5 2.3 had randomized in-lab overnight recordings: baseline nights. Anticipation task resulted higher salivary levels perceived tension, faster heart rate lower vagal activity, based variability measures, both groups women. The manipulation nervous system extended into first 4 h night groups. However, tone recovered 4-6 controls but not group. Sleep macrostructure was unaltered by stress, apart from delayed latency REM Quantitative analysis non-rapid eye movement microstructure revealed greater electroencephalographic (EEG) power beta1 range (15-≤23 Hz), reflecting EEG sleep, compared baseline, flash frequency remained similar nights for These results show impacts before insomnia. Findings also indicate increased lacked recovery activity across suggesting sensitivity this