The Liver in Systemic Illness

摘要: The size of an organ does not always reflect its relevance, but in the case liver, this assumption may be true. liver plays a central role all metabolic processes body. Apart from processing fat, carbohydrates, and proteins to supply energy, is responsible for detoxification protects organism pathogens. Moreover, storage vitamins minerals, particular iron copper, occurs rendering possible their provision times deprivation. It therefore surprising that during course many systemic diseases, gets involved injured. In general, mechanisms cause damage can metabolic, toxic, vascular, or immunologic origin. Despite large variation pathogens affect final result hepato- and/or cholangio-cellular injury either end cirrhosis when chronic failure acute severe damage. Since first step treatment correct diagnosis involvement disease, we aim give overview paediatric illnesses do primarily still more less injury. Treatment underlying disease thereby terminating pathophysiological mechanism lead resolution most cases; nevertheless specific interventions ranging pure observation avoidance certain toxic medications even maximal therapy as transplantation sometimes required.