摘要: In vitro and in vivo studies show that levels of lactate available to neurons affects susceptibility epileptic seizure, a finding consistent with the beneficial effect ketogenic diet treat intractable epilepsy humans.
sci-hub.se 参考文章(5)
Patrick Kwan, Martin J. Brodie, Early Identification of Refractory Epilepsy New England Journal of Medicine. ,vol. 342, pp. 314- 319 ,(2000) , 10.1056/NEJM200002033420503
Narinobu Juge, John A. Gray, Hiroshi Omote, Takaaki Miyaji, Tsuyoshi Inoue, Chiaki Hara, Hisayuki Uneyama, Robert H. Edwards, Roger A. Nicoll, Yoshinori Moriyama, Metabolic Control of Vesicular Glutamate Transport and Release Neuron. ,vol. 68, pp. 99- 112 ,(2010) , 10.1016/J.NEURON.2010.09.002
N. Sada, S. Lee, T. Katsu, T. Otsuki, T. Inoue, Targeting LDH enzymes with a stiripentol analog to treat epilepsy Science. ,vol. 347, pp. 1362- 1367 ,(2015) , 10.1126/SCIENCE.AAA1299
Detlev Boison, The adenosine kinase hypothesis of epileptogenesis Progress in Neurobiology. ,vol. 84, pp. 249- 262 ,(2008) , 10.1016/J.PNEUROBIO.2007.12.002
Elizabeth G Neal, Hannah Chaffe, Ruby H Schwartz, Margaret S Lawson, Nicole Edwards, Geogianna Fitzsimmons, Andrea Whitney, J Helen Cross, The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial The Lancet Neurology. ,vol. 7, pp. 500- 506 ,(2008) , 10.1016/S1474-4422(08)70092-9