Correlation of perioperative platelet function and coagulation tests with bleeding after cardiopulmonary bypass surgery.

摘要: The authors evaluated the correlation of post-cardiopulmonary bypass surgery bleeding, measured as 24-hour chest tube output/kilogram body weight, with platelet function tests using glass bead adhesion and Thrombelastograph Platelet Mapping (Haemoscope Corporation, Niles, Ill); coagulation tests; patient characteristics; parameters; visual assessment surgical field bleeding before closure not (code 1), oozing 2), excessive 3). All indicated significant dysfunction 15 minutes after protamine neutralization heparin. With exception adherence, these assays poor recovery 1 hour postoperatively. By multiple regression, most predictors postoperative were a low mass index (BMI) (P < 0.0001), lowest core temperature = 0.0006), cross clamp time 0.0001). Low was significantly 0.0001) correlated time, which believe is likely cause dysfunction. None bleeding. Looking at highest quartile output patients (n 19) versus upper lower 50th percentile function, could be explained for 11 by BMI plus parameters along and/or In three cases without negative parameters, observed. remaining five did give clear indication primarily responsible