The Biology of Mesenchymal Stem Cells in Health and Disease and Its Relevance to MSC-Based Cell Delivery Therapies

作者: Catherine M. Browne , Tung-Liang Chung , Kerry Atkinson

DOI: 10.1007/978-1-62703-200-1_4

关键词:

摘要: Mesenchymal stromal cells (MSCs) are dynamic that orchestrate tissue morphogenesis during development, support haematopoiesis throughout life, and key mediators of repair disease resolution. In certain states, however, MSCs mediate disrepair exacerbation. Herein we describe the salient features MSCs, highlight need for a deep understanding molecular mechanisms underpin biological function these cells, in order to develop safe effective MSC-based therapies acute chronic disorders currently untreatable.

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