Primary aldosteronism: management issues.

作者: WILLIAM F. YOUNG

DOI: 10.1111/J.1749-6632.2002.TB04413.X

关键词:

摘要: Since its initial description in 1955, primary aldosteronism was thought to be a rare cause of hypertension. However, improved screening methods show that primary aldosteronism is a common form of secondary hypertension. Diagnosis of this disorder results in improved or cured hypertension or targeted pharmacotherapy. Patients with hypertension and hypokalemia and most patients with treatment‐resistant hypertension should undergo screening for primary aldosteronism. A random and ambulatory ratio of plasma aldosterone …

参考文章(52)
Anna M. Sawka, William F. Young, Geoffrey B. Thompson, Clive S. Grant, David R. Farley, Cynthia Leibson, Jon A. van Heerden, Primary aldosteronism: factors associated with normalization of blood pressure after surgery. Annals of Internal Medicine. ,vol. 135, pp. 258- 261 ,(2001) , 10.7326/0003-4819-135-4-200108210-00010
David H.P. Streeten, Nestor Tomycz, Gunnar H. Anderson, Reliability of screening methods for the diagnosis of primary aldosteronism The American Journal of Medicine. ,vol. 67, pp. 403- 413 ,(1979) , 10.1016/0002-9343(79)90786-1
W. Reid Litchfield, Bruce F. Anderson, Ruediger J. Weiss, Richard P. Lifton, Robert G. Dluhy, Intracranial Aneurysm and Hemorrhagic Stroke in Glucocorticoid-remediable Aldosteronism Hypertension. ,vol. 31, pp. 445- 450 ,(1998) , 10.1161/01.HYP.31.1.445
R. D. Gordon, M. Stowasser, T. J. Tunny, S. A. Klemm, J. C. Rutherford, High incidence of primary aldosteronism in 199 patients referred with hypertension. Clinical and Experimental Pharmacology and Physiology. ,vol. 21, pp. 315- 318 ,(1994) , 10.1111/J.1440-1681.1994.TB02519.X
Richard P. Lifton, Robert G. Dluhy, Michael Powers, Glenn M. Rich, Sandra Cook, Stanley Ulick, Jean-Marc Lalouel, A chimaeric 11 beta-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature. ,vol. 355, pp. 262- 265 ,(1992) , 10.1038/355262A0
T. JOSEPH MCKENNA, SAVIO J. SEQUEIRA, ANDREW HEFFERNAN, JOSEPH CHAMBERS, SEAN CUNNINGHAM, Diagnosis under random conditions of all disorders of the renin-angiotensin-aldosterone axis, including primary hyperaldosteronism. The Journal of Clinical Endocrinology and Metabolism. ,vol. 73, pp. 952- 957 ,(1991) , 10.1210/JCEM-73-5-952
DAVID C. KEM, KUEN TANG, CHRISTIAN S. HANSON, RONALD D. BROWN, RONALD PAINTON, MYRON H. WEINBERGER, JOHN W. HOLLIFIELD, The Prediction of Anatomical Morphology of Primary Aldosteronism Using Serum 18-Hydroxycorticosterone Levels* The Journal of Clinical Endocrinology and Metabolism. ,vol. 60, pp. 67- 73 ,(1985) , 10.1210/JCEM-60-1-67
Paolo Mulatero, Franco Veglio, Catia Pilon, Franco Rabbia, Cristina Zocchi, Paolo Limone, Marco Boscaro, Nicoletta Sonino, Francesco Fallo, Diagnosis of Glucocorticoid-Remediable Aldosteronism in Primary Aldosteronism: Aldosterone Response to Dexamethasone and Long Polymerase Chain Reaction for Chimeric Gene The Journal of Clinical Endocrinology and Metabolism. ,vol. 83, pp. 2573- 2575 ,(1998) , 10.1210/JCEM.83.7.4946
Dai Hirohara, Kaoru Nomura, Takahiro Okamoto, Makoto Ujihara, Kazue Takano, Performance of the basal aldosterone to renin ratio and of the renin stimulation test by furosemide and upright posture in screening for aldosterone-producing adenoma in low renin hypertensives The Journal of Clinical Endocrinology and Metabolism. ,vol. 86, pp. 4292- 4298 ,(2001) , 10.1210/JCEM.86.9.7867