Gender-medicine aspects in allergology.

摘要: Despite the identical immunological mechanisms activating release of mediators and consecutive symptoms in immediate-type allergy, there is still a clear clinical difference between female male allergic patients. Even though risk being greater for boys childhood, almost from adolescence onwards it seems to be disadvantage woman as far atopic disorders are concerned. Asthma, food allergies anaphylaxis more frequently diagnosed females. In turn, asthma hay fever associated with irregular menstruation. Pointing towards role sex hormones, an association intake contraceptives, exacerbations during pregnancy have been observed. Moreover, peri- postmenopausal women were reported increasingly suffer asthma, wheeze fever, even enhanced by hormone replacement therapy. This may on account recently identified oestradiol-receptor-dependent mast-cell activation. As paradox nature, become hypersensitive against their own resulting positive reactivity upon intradermal injection oestrogen or progesterone. More importantly, this specific hypersensitivity recurrent miscarriages. striking gender-specific bias IgE-mediated diseases, public awareness fact remains minimal today.