Bacteriological Spectrum of Post Operative Wound Infections and their Antibiogram in a Tertiary Hospital, Dar es salaam, Tanzania

作者: Joel Manyahi

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摘要: Surgical site infection (SSI) is among the most common problem for patients who undergo operative procedures. It remains a and widespread contributing to morbidity mortality; partly attributed increase in infections due antimicrobial resistant bacterial pathogens. In Tanzania there has been limited data regarding magnitude of SSIs pathogens as well pattern antibiotics commonly used treatment these infections. To determine spectrum bacteria isolates from postoperative wound their susceptibility patterns at Muhimbili National Hospital (MNH) Orthopedic Institute (MOI). This was descriptive cross sectional study which conducted with post general surgery obstetrics/gynecology wards MNH Orthopedics Trauma unit MOI. The participants were consecutively recruited surgery, orthopedics trauma MOI September 2011 February, 2012. Structured questionnaires collect social demographic characteristics, clinical history information case notes. Culturing colony characteristics followed by Gram stain provisional identity pathogenic bacteria. Further identification done set biochemical tests, API 20E, VITEK. Antimicrobial isolated determined Kirby Bauer disc diffusion method. Pseudomonas aeruginosa frequently organism Most negative multiply agents tested; but all sensitive carbapenems. Eighty eight percent (88%) enteric gram rods multi-drug resistance. ESBLs production viii detected 92.3% Escherichia coli 69% Klebsiella pneumoniae. Forty four (44%) 18 S. aureus obtained MRSA. isolate SSI. prescribed agents. Also an producing Enterobacteriaceae MRSA strains. Routine culture should be performed whenever SSI suspected choice guided routine sensitivity (including ESBL screening) testing. Ciprofloxacin replace first line empirical SSIs; strict guidelines prescriptions established.

参考文章(64)
Aseffa A, Kotisso B, Surgical wound infection in a teaching hospital in Ethiopia. East African Medical Journal. ,vol. 75, pp. 402- 405 ,(1998)
Behounde T, Mapouka Pa, Guetahoun Y, Bercion R, Gaudeuille A, [Surgical site infection survey in the orthopaedic surgery department of the "Hôpital communautaire de Bangui," Central African Republic]. Bulletin De La Societe De Pathologie Exotique. ,vol. 100, pp. 197- 200 ,(2007)
Koigi-Kamau R, Wanyoike-Gichuhi J, Kabare Lw, Incidence of wound infection after caesarean delivery in a district hospital in central Kenya. East African Medical Journal. ,vol. 82, pp. 357- 361 ,(2005)
Steven M. Opal, Endotoxins and other sepsis triggers. Contributions To Nephrology. ,vol. 167, pp. 14- 24 ,(2010) , 10.1159/000315915
RP Karyakarte, SM Sachdeo, AS Damle, NS Patwardhan, VP Baradkar, LK Bichile, AR Anvikar, JD Kulkarni, AB Deshmukh, JK Bajaj, AK Malik, One year prospective study of 3280 surgical wounds Indian Journal of Medical Microbiology. ,vol. 17, pp. 129- ,(1999)
H. Urassa, M. Battegay, Z. Jeffrey, T. Smith, H. Mshinda, R. Frei, A.F. Widmer, J. Fehr, C. Hatz, I. Soka, P. Kibatala, Antimicrobial prophylaxis to prevent surgical site infections in a rural sub‐Saharan hospital Clinical Microbiology and Infection. ,vol. 12, pp. 1224- 1227 ,(2006) , 10.1111/J.1469-0691.2006.01551.X
Bjørn Blomberg, Davis SM Mwakagile, Willy K Urassa, Samwel Y Maselle, Marcellina Mashurano, Asbjørn Digranes, Stig Harthug, Nina Langeland, Surveillance of antimicrobial resistance at a tertiary hospital in Tanzania BMC Public Health. ,vol. 4, pp. 45- 45 ,(2004) , 10.1186/1471-2458-4-45