CRYPTORCHIDISM AND MALE FERTILITY: A STUDY OF THE DETERMINANTS OF INFERTILITY AMONG FORMERLY CRYPTORCHID AND CONTROL MEN

摘要: Background: Cryptorchidism is a failure of the testis to descend into scrotum from its initial site development in abdomen. The results significant histologic changes testicular tissues and increases risk for infertility cancer. Incidence cryptorchidism approximately 3% at birth declining 1% one year age because spontaneous descent. Little no descent occurs after six months surgical correction by orchiopexy recommended two.Study Cohort: Children's Hospital Pittsburgh Male Fertility Study has been looking impact on male fertility since 1992. study cohort comprises 1405 former cryptorchids control men. Each subjects completed an extensive questionnaire that included questions marriage cohabitation, paternity, health problems, environmental/occupational exposures. A subset full returned adulthood evaluation hormone levels semen analysis (n=167).Results: articles presented here represent selection time conception among formerly cryptorchid men, suture fertility, influence sperm count. Time significantly increased bilateral (33.9 months), but not unilateral men (11.1 months) as compared (8.8 months). Placement transparenchymal during greatly (RR 7.56) Age negatively correlated (r= -0.274) with inhibin B positively (r=0.229) FSH.Conclusions: impacts human male. It can increase reduce counts, especially Surgical technique utilizing placement through future should be avoided. With incidence prevalence year, it represents single most common defect males. public importance leads risks both cancer infertility. Future research focus identifying environmental behavioral causes optimizing treatment.