Neuro‐Nano Interfaces: Utilizing Nano‐Coatings and Nanoparticles to Enable Next‐Generation Electrophysiological Recording, Neural Stimulation, and Biochemical Modulation

作者: Ashlyn T. Young , Neil Cornwell , Michael A. Daniele

DOI: 10.1002/ADFM.201700239

关键词:

摘要: Neural interfaces provide a window into the workings of nervous system-enabling both biosignal recording and modulation. Traditionally, neural have been restricted to implanted electrodes record or modulate electrical activity system. Although these electrode systems are mechanically operationally robust, they limited utility due resultant macroscale damage from invasive implantation. For this reason, novel nanomaterials being investigated enable new strategies chronically interact with system at cellular network level. In feature article, use improve current electrophysiological interfaces, as well nano-interfaces via alternative mechanisms, such remote transduction electromagnetic fields explored. Specifically, article will review nanoparticle coatings enhance function, then an analysis cutting-edge, targeted technologies utilized interface biochemical behavior be provided. Furthermore, emerging, specialized-use case for presented: modulation blood-brain barrier.

参考文章(219)
Pilar Calvo, Bruno Gouritin, Hélène Chacun, Didier Desmaële, Jean D'Angelo, Jean‐Pierre Noel, Dominique Georgin, Elias Fattal, Jean P. Andreux, Patrick Couvreur, Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharmaceutical Research. ,vol. 18, pp. 1157- 1166 ,(2001) , 10.1023/A:1010931127745
Wei Li, Rongcong Luo, Xudong Lin, Amol D. Jadhav, Zicong Zhang, Li Yan, Chung-Yuan Chan, Xianfeng Chen, Jufang He, Chia-Hung Chen, Peng Shi, Remote modulation of neural activities via near-infrared triggered release of biomolecules. Biomaterials. ,vol. 65, pp. 76- 85 ,(2015) , 10.1016/J.BIOMATERIALS.2015.06.041
Valeria Amenta, Karin Aschberger, Carbon nanotubes: potential medical applications and safety concerns Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. ,vol. 7, pp. 371- 386 ,(2015) , 10.1002/WNAN.1317
Joyce Breger, James B. Delehanty, Igor L. Medintz, Continuing progress toward controlled intracellular delivery of semiconductor quantum dots Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. ,vol. 7, pp. 131- 151 ,(2015) , 10.1002/WNAN.1281
Diego Ghezzi, Maria Rosa Antognazza, Marco Dal Maschio, Erica Lanzarini, Fabio Benfenati, Guglielmo Lanzani, A hybrid bioorganic interface for neuronal photoactivation Nature Communications. ,vol. 2, pp. 166- ,(2011) , 10.1038/NCOMMS1164
Seung Won Shin, In Hyun Song, Soong Ho Um, Role of Physicochemical Properties in Nanoparticle Toxicity Nanomaterials. ,vol. 5, pp. 1351- 1365 ,(2015) , 10.3390/NANO5031351
Tianshu Wu, Ting Zhang, Yilu Chen, Meng Tang, Research advances on potential neurotoxicity of quantum dots. Journal of Applied Toxicology. ,vol. 36, pp. 345- 351 ,(2016) , 10.1002/JAT.3229
Feng Wang, Yuan Cheng, Jie Mei, Yu Song, Yan-qing Yang, Yingjiang Liu, Zhibiao Wang, Focused Ultrasound Microbubble Destruction-Mediated Changes in Blood-Brain Barrier Permeability Assessed by Contrast-Enhanced Magnetic Resonance Imaging Journal of Ultrasound in Medicine. ,vol. 28, pp. 1501- 1509 ,(2009) , 10.7863/JUM.2009.28.11.1501
Theodore A. Henderson, Larry Morries, Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain? Neuropsychiatric Disease and Treatment. ,vol. 11, pp. 2191- 2208 ,(2015) , 10.2147/NDT.S78182
Ralph Weissleder, A clearer vision for in vivo imaging. Nature Biotechnology. ,vol. 19, pp. 316- 317 ,(2001) , 10.1038/86684