Is cerebral spinal fluid flow associated with body mass index and head circumference in healthy children? A phase contrast magnetic resonance imaging study

摘要: The aim of this study was to investigate the relationship between age, gender, body mass index (BMI), and head circumference (HC) cerebral spinal fluid (CSF) flow dynamics in pediatric population. prospective included a total 137 participants, 75 boys 62 girls, ranging age from 2 204 months. Quantitative evaluation CSF made by using phase contrast magnetic resonance imaging (PC-MRI) axial plane at level aqueductus cerebri. Flow were recorded as peak mean velocity (cm/s); cranial, caudal, net volume (ml); cerebri area (mm2). Correlation baseline descriptive parameters, including BMI, HC, aforementioned investigated. significantly lower girls (p = 0.002). There no association aqueduct area, velocity, cranial volume. remarkably higher children 0.03), whereas found be infants 0.04 p 0.03, respectively). Notably, cases with HC below normal values had 0.01, 0.04, BMI indicators PC-MRI. may associated children. A smaller is accompanied forward volume, reverse aqueductal diameter. These points should remembered during design further trials on determinants