Mustererkennung zur Differenzialdiagnose lymphoepithelialer Läsionen der Speicheldrüsen

摘要: The prototype of a salivary lymphoepithelial lesion is the autoimmune disease Sjogren's syndrome with characteristic duct lesions (LEL). distinction from cases initial transformation into associated marginal zone B-cell lymphoma (MALT type) can be very challenging, whereby presence small "halos" lead to over-diagnosis. HIV-associated cystic histologically almost identical and often needs clinical correlation. sporadic cyst parotid gland frequent finding has no consequence; however, this entity identified distinguished above-mentioned entities. most diagnosis in resected submandibular glands chronic-fibrosing sialadenitis, so-called Kuttner's tumour. Altogether, there wide spectrum interaction area glands, including biphasic tumours an obligate lymphoid component, epithelial facultative tumour-associated proliferation, different processes intraparotid lymph nodes. immunohistological reaction for pan-keratin helpful thorough pattern analysis lesions. relative frequency also diagnostically helpful.