Antibodies Directed to Angiopoietin-1 and Angiopoietin-2 and Uses Thereof
作者： Jonathan D. Oliner , Thomas C. Boone
DOI:
关键词:
摘要: Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin 1 and/or angiopoietin-2. Also disclosed heavy chain fragments, light and CDRs of the well methods making using antibodies.
lens.org参考文章(310)
Atsushi Otani, Hideyasu Oh, Shinji Koyama, Miyo Matsumura, Hitoshi Takagi, Yoshihito Honda, Expressions of angiopoietins and Tie2 in human choroidal neovascular membranes. Investigative Ophthalmology & Visual Science. ,vol. 40, pp. 1912- 1920 ,(1999)
A. Lesk, Computational molecular biology Oxford University Press, Inc.. ,(1988)
George D. Yancopoulos, Guillermo García-Cardeña, Andreas Papapetropoulos, Peter C. Maisonpierre, Thomas J. Dengler, William C. Sessa, Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors. Laboratory Investigation. ,vol. 79, pp. 213- 223 ,(1999)
Mepur H. Ravindranath, Donald L. Morton, Sialyl lewis antigens as targets for immunotherapy ,(1998)
R. A. Reisfeld, S. Sell, Monoclonal antibodies and cancer therapy UCLA symposium on molecular and cellular biology. Annual meeting. 14. pp. 33- 74 ,(1985)
José M. Carballido, Reiko Namikawa, Nicole Carballido-Perrig, Svetlana Antonenko, Maria-Grazia Roncarolo, Jan E. de Vries, Generation of primary antigen-specific human T- and B-cell responses in immunocompetent SCID-hu mice. Nature Medicine. ,vol. 6, pp. 103- 106 ,(2000) , 10.1038/71434
David R. Hinton, Masanori Hangai, Stephen J. Ryan, Toshinori Murata, Shikun He, Christine Spee, Nobuaki Miyawaki, Jennifer I. Lim, Angiopoietin-1 upregulation by vascular endothelial growth factor in human retinal pigment epithelial cells Investigative Ophthalmology & Visual Science. ,vol. 42, pp. 1617- 1625 ,(2001)
David J. Asai, Antibodies in cell biology Academic Press Inc.. ,(1993)
Hugh G. Griffin, Annette M. Griffin, Computer analysis of sequence data. Methods of Molecular Biology. ,vol. 24, pp. 1- 8 ,(1994) , 10.1385/0-89603-246-9:1
Kalish Susan Croll, Angiopoietins and methods of use thereof ,(2002)