Nano SiO2 and MgO improve the properties of porous β-TCP scaffolds via advanced manufacturing technology.
作者： Chengde Gao , Pingpin Wei , Pei Feng , Tao Xiao , Cijun Shuai
DOI: 10.3390/IJMS16046818
关键词:
摘要: Nano SiO2 and MgO particles were incorporated into β-tricalcium phosphate (β-TCP) scaffolds to improve the mechanical biological properties. The porous cylindrical β-TCP doped with 0.5 wt % SiO2, 1.0 MgO, + fabricated via selective laser sintering respectively undoped scaffold was also prepared as control. phase composition strength of evaluated. X-ray diffraction analysis indicated that transformation from α-TCP inhibited after addition MgO. compressive improved 3.12 ± 0.36 MPa 5.74 0.62 (β-TCP/SiO2), 9.02 0.55 (β-TCP/MgO) 10.43 0.28 (β-TCP/SiO2/MgO), respectively. weight loss apatite-forming ability evaluated by soaking them in simulated body fluid. results demonstrated both dopings slowed down degradation rate bioactivity scaffolds. In vitro cell culture studies facilitated attachment proliferation. Combined found optimal enhancing properties scaffold.
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