Asymmetric functionalization of gold nanoparticles with oligonucleotides.

作者： Xiaoyang Xu , Nathaniel L. Rosi , Yuhuang Wang , Fengwei Huo , Chad A. Mirkin

DOI: 10.1021/JA061980B

关键词:

摘要: Gold nanoparticles (AuNPs) were anisotropically functionalized with two different oligonucleotide sequences using magnetic microparticles as geometric restriction templates for site-selective enzymatic extension of particle-bound oligonucleotides. The divalent linking capability the resulting AuNPs allowed design and programmable assembly discrete nanoparticle heterostructures.