When is lymph node biopsy indicated in children with enlarged peripheral nodes

摘要: To better define the indications for diagnostic biopsy, 239 children who underwent peripheral lymph node biopsy were reviewed. The duration of lymph-adenopathy by history, consistency nodes, and presence more than one site palpable adenopathy not specific in differentiating serious diseases involving nodes from reactive hyperplasia. differential diagnosis causes enlargement is approached based on child's age, location adenopathy, or absence fixation tenderness. Most with supraclavicular sick fever week's weight loss which a readily made, some to overlying skin should undergo early biopsy. Excluding above findings, when apparent, serial measurements ruler over several weeks appears be most reasonable method, at present time, discriminating hyperplastic that are involved progressive disease process.