Engineering dendritic cell grafts for clinical trials in cellular immunotherapy of cancer: example of chronic myelogenous leukemia.
作者： Gastineau Da , Dietz Ab , Vuk-Pavlović S , Litzow Mr
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摘要: Dendriticcellsarepivotalregulatorsofimmunereactivityandimmunetolerance.TheobservationthatdendriticcellscanrecruitnaiveT-cellshasinvigoratedcancerimmunologyandstimulatedclinicaltrialsofdendriticcellsinimmuno -therapy. However, variables inherent in preparation and use of dendritic cell grafts remain to be tested. Here we dis -cusstheroleof
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