Seizures due to lidocaine toxicity in a child during cardiac catheterization.
作者： C. Anthony Ryan , Murray Robertson , J. Yashu Coe
DOI: 10.1007/BF00796991
关键词:
摘要: A 17-month-old boy developed grand mal seizures secondary to lidocaine toxicity during balloon dilatation of a congenital pulmonary valve stenosis. Lidocaine at 38 mg/kg (nine times the recommended maximum dose 4.5 mg/kg) was administered 90-min period in order optimize local anesthesia. This resulted toxic serum levels (8.7 mg/L; therapeutic range, 1.5–5 mg/L) time seizures. Caution should be exercised with anesthetics invasive cardiac catheterizations. Hypercarbia (which lowers seizure threshold anesthetics) avoided and temptation exceed resisted.
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Rudolph H. de Jong, Irving H. Wagman, David A. Prince, Effect of carbon dioxide on the cortical seizure threshold to lidocaine Experimental Neurology. ,vol. 17, pp. 221- 232 ,(1967) , 10.1016/0014-4886(67)90147-1
Herbert E. Cohn, Michael D. Freed, William F. Hellenbrand, Donald C. Fyler, Complications and mortality associated with cardiac catheterization in infants under one year: A prospective study Pediatric Cardiology. ,vol. 6, pp. 123- 131 ,(1985) , 10.1007/BF02336550
Howard C. Mofenson, Thomas R. Caraccio, Harvey Miller, Joseph Greensher, Lidocaine Toxicity from Topical Mucosal Application Clinical Pediatrics. ,vol. 22, pp. 190- 192 ,(1983) , 10.1177/000992288302200306
A. P. Jonville, P. Barbier, M. H. Blond, M. Boscq, E. Autret, M. Breteau, Accidental lidocaine overdosage in an infant Clinical Toxicology. ,vol. 28, pp. 101- 106 ,(1990) , 10.3109/15563659008993480
Peter Rothstein, Jeffrey Dornbusch, Bennett A. Shaywitz, Prolonged seizures associated with the use of viscous lidocaine The Journal of Pediatrics. ,vol. 101, pp. 461- 463 ,(1982) , 10.1016/S0022-3476(82)80088-7
Dante Antonelli, Moshe Ben-Ami, Zvi Weiss, Sinus standstill following accidental lidocaine overdose American Heart Journal. ,vol. 107, pp. 1042- 1044 ,(1984) , 10.1016/0002-8703(84)90855-X
Elias Badui, David Garcia-Rubi, Bruno Estañol, Inadvertent massive lidocaine overdose causing temporary complete heart block in myocardial infarction American Heart Journal. ,vol. 102, pp. 801- 803 ,(1981) , 10.1016/0002-8703(81)90115-0
John M. Palmisano, Jon N. Meliones, Dennis C. Crowley, Jean M. Martin, Kim H. Truman, Brad A. Krauzowicz, Albert P. Rocchini, Lidocaine toxicity after subcutaneous infiltration in children undergoing cardiac catheterization American Journal of Cardiology. ,vol. 67, pp. 647- 648 ,(1991) , 10.1016/0002-9149(91)90908-4
Wolf D. Dettbarn, The active form of local anesthetics Biochimica et Biophysica Acta. ,vol. 57, pp. 73- 76 ,(1962) , 10.1016/0006-3002(62)91079-X
Philip W. Lebowitz, Georoe Psarras, M. Ramez Salem, Clinical Anesthesia Procedures of the Massachusetts General Hospital Anesthesiology. ,vol. 50, pp. 176- 176 ,(1979) , 10.1097/00000542-197902000-00033