Oxidative sp3 C–H Functionalization of Methyl Substituted Aza-Aromatics: An Easy Access to N-Fused Polyheterocycles

Lijuan Ma, Xianpei Wang, Wei Yu, Bing Han, TBAI-catalyzed oxidative coupling of aminopyridines with β-keto esters and 1,3-diones—synthesis of imidazo[1,2-a]pyridines Chemical Communications. ,vol. 47, pp. 11333- 11335 ,(2011) , 10.1039/C1CC13568F

Hui Xu, Ling-ling Fan, Synthesis and antifungal activities of novel 5,6-dihydro-indolo[1,2-a]quinoxaline derivatives. European Journal of Medicinal Chemistry. ,vol. 46, pp. 1919- 1925 ,(2011) , 10.1016/J.EJMECH.2011.02.035

Jean M Chezal, Emmanuel Moreau, Olivier Chavignon, Claire Lartigue, Yves Blache, Jean C Teulade, Efficient synthesis of novel dipyridoimidazoles and pyrido[1′,2′;1,2]imidazo[4,5-d]pyridazine derivatives Tetrahedron. ,vol. 59, pp. 5869- 5878 ,(2003) , 10.1016/S0040-4020(03)00938-4

Wen-Bin Wu, Jing-Mei Huang, Highly regioselective C-N bond formation through C-H azolation of indoles promoted by iodine in aqueous media. Organic Letters. ,vol. 14, pp. 5832- 5835 ,(2012) , 10.1021/OL302609M

Qi Chao, Kelly G. Sprankle, Robert M. Grotzfeld, Andiliy G. Lai, Todd A. Carter, Anne Marie Velasco, Ruwanthi N. Gunawardane, Merryl D. Cramer, Michael F. Gardner, Joyce James, Patrick P. Zarrinkar, Hitesh K. Patel, Shripad S. Bhagwat, Identification of N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-like tyrosine kinase-3 (FLT3) inhibitor. Journal of Medicinal Chemistry. ,vol. 52, pp. 7808- 7816 ,(2009) , 10.1021/JM9007533

Jean Guillon, Robert C. Reynolds, Jean-Michel Leger, Marie-Aude Guie, Stephane Massip, Patrick Dallemagne, Christian Jarry, Synthesis and PreliminaryIn Vitro Evaluation of Antimycobacterial Activity of New Pyrrolo[1,2-a]quinoxaline-carboxylic Acid Hydrazide Derivatives Journal of Enzyme Inhibition and Medicinal Chemistry. ,vol. 19, pp. 489- 495 ,(2004) , 10.1080/14756360412331280464

A. Gomtsyan, Heterocycles in drugs and drug discovery Chemistry of Heterocyclic Compounds. ,vol. 48, pp. 7- 10 ,(2012) , 10.1007/S10593-012-0960-Z

Huihui Fang, Xiaoyu Wu, Linlin Nie, Xiaoyang Dai, Jie Chen, Weiguo Cao, Gang Zhao, Diastereoselective syntheses of indoloquinolizidines by a Pictet-Spengler/lactamization cascade. Organic Letters. ,vol. 12, pp. 5366- 5369 ,(2010) , 10.1021/OL101922H

Jinglin Liu, Qun Dang, Zhonglin Wei, Hengbin Zhang, Xu Bai, Parallel solution-phase synthesis of a 2,6,8,9-tetrasubstituted purine library via a sulfur intermediate. ACS Combinatorial Science. ,vol. 7, pp. 627- 636 ,(2005) , 10.1021/CC049819P

Jinglin Liu, Qun Dang, Zhonglin Wei, Fuqiang Shi, Xu Bai, An efficient and regiospecific strategy to N7-substituted purines and its application to a library of trisubstituted purines. ACS Combinatorial Science. ,vol. 8, pp. 410- 416 ,(2006) , 10.1021/CC060009I