Polymerization of Peptide Polymers for Biomaterial Applications

摘要: The term biomaterial, as defined by a consensus conference on Definitions in Biomaterial Science, is material intended to interface with biological systems evaluate, treat, augment or replace any tissue, organ of function the body. [1] Biomaterials range from simple embedded complex functional devices. There are three primary types biomaterials: 1) metallic, based metallic bonds, 2) ceramic, ionic and 3) polymeric, covalent bonds. [2] Polymers that mechanical resistance, degradable, permeable, soluble transparent, have been used both biomaterial applications. [3-5] properties poly(esters), poly(amides), poly(amidoamines), poly(methyl methacrylate), poly(ethyleneimine), particularly well suited (Table 1). These polymeric materials given rise first secondgeneration biomaterials. [6] ‘Next’-generation biomaterials will less toxic degradation products, undergo hierarchal assemble form supramolecular structures, maintain sustainable design. products synthetic polymers acidic cannot be metabolized systems. This can result bioaccumulation these offsetting homeostatic balance system. production requires bulk separation crystallization, which often inhibits formation higher ordered structures. Finally, source for petrochemicals. dependency petrochemicals presents environmental sustainability concerns. development overcome limitations would significant advancement field