Synthetic biology: understanding biological design from synthetic circuits

作者: Shankar Mukherji , Alexander van Oudenaarden

DOI: 10.1038/NRG2697

关键词:

摘要: An important aim of synthetic biology is to uncover the design principles natural biological systems through rational gene and protein circuits. Here, we highlight how process engineering - from promoters control cell-cell interactions has contributed our understanding endogenous are put together function. Synthetic devices allow us grasp intuitively ranges behaviour generated by simple circuits, such as linear cascades interlocking feedback loops, well exert over processes, expression population dynamics.

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