Multifunctional compounds containing organic nitrates, prototypes of hybrid medicaments
作者： I V Serkov , V V Bezuglov
DOI: 10.1070/RC2009V078N05ABEH004024
关键词:
摘要: A modern trend in medical chemistry is the design of multifunctional medicaments with an extensive spectrum action. The review considers one routes to such merdicaments: introduction nitrogen monoxide-generating enzymes into molecules known drugs. Examples synthesis and results biological activity assays for O-nitro derivatives various drugs are presented. Bibliography — 146 references.
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