Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal
作者： Constantinos Tsangarakis , Ioannis N. Lykakis , Manolis Stratakis
DOI: 10.1021/JO7024527
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摘要: The sesquiterpene nanaimoal was synthesized in 21% overall yield and a biomimetic manner. As key step, the acid-catalyzed cyclization of farnesal under zeolite NaY confinement conditions used. intrazeolite affords as major product double-bond isomer nanaimoal, via novel diastereoselective tandem 1,5-diene cyclization/Prins-type reaction.
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