Identification and actions of gastric inhibitory polypeptide.

摘要: Publisher Summary This chapter gives an overview of the identification and actions gastric inhibitory polypeptide (GIP). It describes experiment in which it is concluded that exogenous or endogenous GIP capable insulinotropic effects normal man can lead to substantial acceleration disposal glucose. Because released into blood during absorption glucose response demonstrable on infusion directly intestine after ingestion glucose, this peptide fully qualified take part potentiation insulin secretion from gut man. The findings clearly do not exclude possibility other humoral secretions participate under physiological conditions. However, apparently doses strongly suggest agent accounting for a major attributed intestine.