Evaluation of mithramycin in the treatment of anaplastic gliomas.
作者： Michael D. Walker , Eben Alexander , William E. Hunt , Carl M. Leventhal , M. Stephen Mahaley
DOI: 10.3171/JNS.1976.44.6.0655
关键词:
摘要: ✓ A controlled, prospective, randomized study evaluated the use of mithramycin in treatment anaplastic glioma compared to a similar group patients receiving best conventional care. From total 116 study, 96 were within valid group. All operated on, had histological confirmation glioma, and received radiotherapy at discretion principal investigator. Fifty-two dose 25 µg/kg/day for 21 days, while 44 control There was no significant difference median survival from time randomization those (21 weeks) as not (26 weeks). between two groups relation age distribution, sex, location, diagnosis, tumor characteristics, signs or symptoms, received. Duration symptoms correlates positively with also significantly longer in...
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