Effects of carbohydrate type and concentration and solution osmolality on water absorption.

作者: XIACOAI SHI , ROBERT W. SUMMERS , HAROLD P. SCHEDL , SHAWN W. FLANAGAN , RAYTAI CHANG

DOI: 10.1249/00005768-199512000-00005

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摘要: We studied intestinal absorption of solutions containing either one (glucose, Glu, or maltodextrin, Mal) two (fructose, Fru, and Glu sucrose, Suc) transportable carbohydrate (CHO) substrates using segmental perfusion technique in eight healthy male subjects. These CHO were free directly monosaccharides (Glu, Fru), bound as the disaccharide (sucrose, Suc), oligomers (maltodextrins, Mal). [CHO] was varied from 6% to 8% (120-444 mmol.1(-1)). All contained low [Na+] (15-19 mEq) [K+] (3-4 mEq). Solutions osmolalities 165 477 mOsm.kg(-1). Osmolalities test segment ranged 268 314 The regression line osmolality with water differed for single compared multiple substrate solutions. significantly different intercepts these lines suggest that produce greater at a given than those one. Comparing all solutions, solute flux (partial r = 0.69) more important mean 0.32). In conclusion, stimulate several mechanisms yielding only substrate.

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