Plasma phospholipid essential fatty acids and prostaglandins in alcoholic, habitually violent, and impulsive offenders

作者: Matti E. Virkkunen , David F. Horrobin , Douglas K. Jenkins , Mehar S. Manku

DOI: 10.1016/0006-3223(87)90051-5

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摘要: Abstract Plasma phospholipid essential fatty acids and some of their main metabolites, prostaglandins, were measured among habitually violent impulsive male offenders, who all had alcohol abuse problems, nonviolent control persons. Linoleic acid (18: 2n-6), the precursor n-6 acids, was below normal in intermittent explosive disorder, but dihomogammalinolenic (DGLA) (20: 3n-6) subsequent at same time elevated offenders. Also, a monounsaturate, oleic 1n-9) elevated. The high DGLA correlated with low cholesterol level disorder. arachidonic metabolites PGE 2 TxB antisocial personality. 1 /DGLA ratio number registered crimes suicidal attempts values. possibility that is connected free pool, therefore formation, these offenders discussed.

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