The Swedish Reflux Trial in Children: II. Vesicoureteral Reflux Outcome

作者: Gundela Holmdahl , Per Brandström , Göran Läckgren , Ulla Sillén , Eira Stokland

DOI: 10.1016/J.JURO.2010.01.059

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摘要: Purpose: We compared reflux status in children with dilating vesicoureteral treated 3 groups, including low dose antibiotic prophylaxis, endoscopic therapy and a surveillance group on treatment only for febrile urinary tract infection.Materials Methods: A total of 203 1 to younger than 2 years grade III–IV were recruited into this open, randomized, controlled trial. Endoscopic was done dextranomer/hyaluronic acid copolymer. The main end point after years. Data analyzed by the intent treat principle.Results: Reflux improved all arms. Of patients groups 39%, 71% 47%, respectively, had resolution or downgrading I–II This significantly more common prophylaxis (p = 0.0002 0.0030, respectively). After injections 86% h...

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