A new pyrazole-carboxamide type synthetic cannabinoid AB-CHFUPYCA (N-(1-amino-3-methyl-1-oxobutan-2-yl)-1- (cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5- carboxamide) identified in illegal products
作者： Nahoko Uchiyama , Kazuhiro Asakawa , Ruri Kikura-Hanajiri , Taizo Tsutsumi , Takashi Hakamatsuka
DOI: 10.1007/S11419-015-0283-8
关键词:
摘要: A new pyrazole-carboxamide type synthetic cannabinoid, AB-CHFUPYCA (1), was detected in illegal herbal products by our ongoing survey Japan. The structure of 1 identified gas chromatography–mass spectrometry (GC–MS), liquid (LC–MS), chromatography–high-resolution-mass (LC–HR-MS) and nuclear magnetic resonance (NMR) analyses. Compound showed a molecular weight 400, accurate mass measurement using LC–HR-MS revealed its formula to be C22H29N4O2F. MS NMR spectrometric data that the N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide. 1, which is has 3-(4-fluorophenyl)-1H-pyrazole group place 1H-indazole AB-CHMINACA. To knowledge, on chemistry pharmacology compound have never been reported, we therefore named “AB-CHFUPYCA.”
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