Prognostic importance of weight loss in patients with coronary heart disease regardless of initial body mass index.

作者: Justo Sierra-Johnson , Abel Romero-Corral , Virend K. Somers , Francisco Lopez-Jimenez , Randal J. Thomas

DOI: 10.1097/HJR.0B013E3282F48348

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摘要: BackgroundRecently, mild elevations in body mass index (BMI) have been related to better outcomes patients with coronary heart disease. Our aim was determine whether disease who are participating cardiac rehabilitation would improved if they lost weight and this depend on initial BMI.MethodsThis is a prospective cohort study of 377 consecutive enrolled at program, aged 30–85 years mean follow-up 6.4 ± 1.8 years. We measured total mortality, acute cardiovascular events (fatal nonfatal myocardial infarction, fatal stroke, emergent revascularization the setting unstable angina, hospitalization for congestive failure) composite outcome (mortality + events). Statistical testing used Cox Proportional Hazards Regression.ResultsOn average, loss group (n = 220) 3.6 4.1 kg, nonweight 157) gained 1.5 1.4 k...

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