Two-dimensional electrophoresis of human plasma apolipoproteins.

摘要: The two-dimensional electrophoretic method with silver staining we describe better resolves plasma apolipoproteins (apo) than any procedure previously described. It can be used to screen for abnormalities in apoA-I, apoA-II, apoA-IV, apoC-II, apoC-III, apoD, apoE, and apoH. In addition, this is the first presentation of apoD apoH on gels. This will permit quantification by computer imaging. Such detailed analysis should provide a understanding apolipoprotein function role these play lipoprotein metabolism pathophysiology dyslipoproteinemias coronary artery disease.