Ultrafine particles in human lung macrophages.

摘要: Abstract As knowledge about size dependency of particle toxicity continues to grow, attention has been focused on ultrafine particles (i.e., < 0.1 μm in diameter). In recent studies with rats, investigators learned that likely have greater pulmonary than larger particles, and it is possible exposure to, accumulation of, these the human lung may be associated adverse respiratory health effects. part an ongoing study, authors performed bronchoalveolar lavage 14 healthy current nonsmokers investigate extent which were present macrophages. addition, 10 subjects function tests. Eleven utility workers, 3 nonmaintenance employees a university. The used Zeiss CEM902 electron microscope study macrophages isolated from fluid. Morphometric quantification revealed al...